ChemicalBook > CAS DataBase List > Polygalacic acid
Polygalacic acid
- Product Name
- Polygalacic acid
- CAS No.
- 22338-71-2
- Chemical Name
- Polygalacic acid
- Synonyms
- Polygalacic;Polygalacicaci;Polygalacic acid;Virgaureagenin G;Polygalacic acid, >=98%;Virgaureagenin G，Polygalacic acid;(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid;Polygalacic acid, 98%, from Polygala tenuifolia Willd.;(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid;Olean-12-en-28-oicacid, 2,3,16,23-tetrahydroxy-, (2β,3β,4,16)-
- CBNumber
- CB21040708
- Molecular Formula
- C30H48O6
- Formula Weight
- 504.7
- MOL File
- 22338-71-2.mol
More
Less
Polygalacic acid Property
- Melting point:
- 300-305 °C (sublm)
- Boiling point:
- 638.1±55.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.41±0.70(Predicted)
More
Less
Safety
- HS Code
- 29163990
More
Less
N-Bromosuccinimide Price
Usbiological
- Product number
- 300805
- Product name
- Polygalacic acid
- Packaging
- 20mg
- Price
- $490
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- SHG0005843
- Product name
- (2B,3B,4A,16A)-2,3,16,23-TETRAHYDROXYOLEAN-12-EN-28-OIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.58
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 74064
- Product name
- Polygalacicacid
- Purity
- 98%
- Packaging
- 20mg
- Price
- $533
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb105678
- Product name
- Polygalacic acid
- Purity
- >98%,Standard References Grade
- Packaging
- 20mg
- Price
- $569.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb594205
- Product name
- Virgaureagenin G
- Packaging
- 5mg
- Price
- $596.7
- Updated
- 2021/12/16
More
Less
Polygalacic acid Chemical Properties,Usage,Production
Uses
Polygalacic acid can be used to calm the nerves, eliminate phlegm, reduce swelling, etc. It is mostly used clinically to treat bronchitis, induce labor, and induce labor.
Biological Activity
Polygalacic acid is a triterpenoid tetrahydroxy acid isolated from Polygala paenea L.. It (0-100μM; 24h) can significantly reduce the mRNA expression of MMP-3, MMP-9, MMP-13 and COX-2, and the expression of these factors can be significantly increased by IL-1β in a dose-dependent manner .
in vitro
Polygalacic acid (0-100 μM; 24 hours) significantly decreases the mRNAexpressions of MMP-3, MMP-9, MMP-13, and COX-2, which are significantly increased by IL-1β, in a In a dose-dependent manner. Polygalacic acid (0-100 μM; 6 hours) decreases the expression of phosphor-p38, phosphor-Erk, and phosphor-Jnk induced by IL-1β, phosphor-p65 is not reduced by polygalacic acid.
RT-PCR
| Cell Line: | Chondrocyte cells |
| Concentration: | 50 μM; 100 μM |
| Incubation Time: | 24 hours |
| Result: | Suppressed IL-1β-induced COX-2, MMP3, MMP9, and MMP13 mRNA expression. |
Western Blot Analysis
| Cell Line: | Chondrocyte cells | Concentration: | 50 μM; 100 μM |
| Incubation Time : | 6 hours |
| Result: | Inhibited the IL-1β-induced activation of the MAPK pathway in chondrocytes. |
Polygalacic acid Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Polygalacic acid Suppliers
More
Less
View Lastest Price from Polygalacic acid manufacturers
Career Henan Chemical Co
- Product
- Polygalacic acid 22338-71-2
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24
22338-71-2, Polygalacic acidRelated Search:
2,2-Dimethoxy-2-phenylacetophenone
Diosgenin
Betulin
2-Amino-4-chloro-5-methylbenzenesulfonic acid
Stearic acid
Folic acid
Citric acid
Ethyl 2-(Chlorosulfonyl)acetate
SENEGENIN
Polygalacin D
Sinegin 3
Hosenkoside G
Vindolinine
Kushenol I
Dipsanoside B
(6R,7S,8S)-5,6,7,8-Tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-2-naphthalenol
kuwanon H
Gymnemagenin